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Simvastatin inhibits neural cell apoptosis and promotes locomotor recovery via activation of Wnt/β‐catenin signaling pathway after spinal cord injury

Statins exhibit neuroprotective effects after spinal cord injury (SCI). However, the molecular mechanism underlying these effects remains unknown. This study demonstrates that the hydroxymethylglutaryl coenzyme A reductase inhibitor simvastatin (Simv) exhibits neuroprotective effects on neuronal apo...

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Foilsithe in:J Neurochem
Main Authors: Gao, Kai, Shen, Zhaoliang, Yuan, Yajiang, Han, Donghe, Song, Changwei, Guo, Yue, Mei, Xifan
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5089634/
https://ncbi.nlm.nih.gov/pubmed/26443048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13382
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