Simvastatin inhibits neural cell apoptosis and promotes locomotor recovery via activation of Wnt/β‐catenin signaling pathway after spinal cord injury

Statins exhibit neuroprotective effects after spinal cord injury (SCI). However, the molecular mechanism underlying these effects remains unknown. This study demonstrates that the hydroxymethylglutaryl coenzyme A reductase inhibitor simvastatin (Simv) exhibits neuroprotective effects on neuronal apo...

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Detaylı Bibliyografya
Yayımlandı:J Neurochem
Asıl Yazarlar: Gao, Kai, Shen, Zhaoliang, Yuan, Yajiang, Han, Donghe, Song, Changwei, Guo, Yue, Mei, Xifan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2016
Konular:
ORIGINAL ARTICLES
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5089634/
https://ncbi.nlm.nih.gov/pubmed/26443048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13382
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