Simvastatin inhibits neural cell apoptosis and promotes locomotor recovery via activation of Wnt/β‐catenin signaling pathway after spinal cord injury

Statins exhibit neuroprotective effects after spinal cord injury (SCI). However, the molecular mechanism underlying these effects remains unknown. This study demonstrates that the hydroxymethylglutaryl coenzyme A reductase inhibitor simvastatin (Simv) exhibits neuroprotective effects on neuronal apo...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Neurochem
Hlavní autoři: Gao, Kai, Shen, Zhaoliang, Yuan, Yajiang, Han, Donghe, Song, Changwei, Guo, Yue, Mei, Xifan
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
ORIGINAL ARTICLES
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5089634/
https://ncbi.nlm.nih.gov/pubmed/26443048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13382
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky