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A BOILED‐Egg To Predict Gastrointestinal Absorption and Brain Penetration of Small Molecules

Apart from efficacy and toxicity, many drug development failures are imputable to poor pharmacokinetics and bioavailability. Gastrointestinal absorption and brain access are two pharmacokinetic behaviors crucial to estimate at various stages of the drug discovery processes. To this end, the Brain Or...

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Podrobná bibliografie
Vydáno v:ChemMedChem
Hlavní autoři: Daina, Antoine, Zoete, Vincent
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5089604/
https://ncbi.nlm.nih.gov/pubmed/27218427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201600182
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