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A BOILED‐Egg To Predict Gastrointestinal Absorption and Brain Penetration of Small Molecules

Apart from efficacy and toxicity, many drug development failures are imputable to poor pharmacokinetics and bioavailability. Gastrointestinal absorption and brain access are two pharmacokinetic behaviors crucial to estimate at various stages of the drug discovery processes. To this end, the Brain Or...

詳細記述

保存先:
書誌詳細
出版年:ChemMedChem
主要な著者: Daina, Antoine, Zoete, Vincent
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5089604/
https://ncbi.nlm.nih.gov/pubmed/27218427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201600182
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