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A BOILED‐Egg To Predict Gastrointestinal Absorption and Brain Penetration of Small Molecules

Apart from efficacy and toxicity, many drug development failures are imputable to poor pharmacokinetics and bioavailability. Gastrointestinal absorption and brain access are two pharmacokinetic behaviors crucial to estimate at various stages of the drug discovery processes. To this end, the Brain Or...

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Detalhes bibliográficos
Publicado no:ChemMedChem
Main Authors: Daina, Antoine, Zoete, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5089604/
https://ncbi.nlm.nih.gov/pubmed/27218427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201600182
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