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A BOILED‐Egg To Predict Gastrointestinal Absorption and Brain Penetration of Small Molecules
Apart from efficacy and toxicity, many drug development failures are imputable to poor pharmacokinetics and bioavailability. Gastrointestinal absorption and brain access are two pharmacokinetic behaviors crucial to estimate at various stages of the drug discovery processes. To this end, the Brain Or...
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| Veröffentlicht in: | ChemMedChem |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5089604/ https://ncbi.nlm.nih.gov/pubmed/27218427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201600182 |
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