beta2-glycoprotein-I (apolipoprotein H) and beta2-glycoprotein-I-phospholipid complex harbor a recognition site for the endocytic receptor megalin.

Screening of serum by using a surface plasmon resonance analysis assay identified beta2-glycoprotein-I/apolipoprotein H as a plasma component binding to the renal epithelial endocytic receptor megalin. A calcium-dependent megalin-mediated beta2-glycoprotein-I endocytosis was subsequently demonstrate...

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Dettagli Bibliografici
Autori principali: Moestrup, S K, Schousboe, I, Jacobsen, C, Leheste, J R, Christensen, E I, Willnow, T E
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1998
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC508955/
https://ncbi.nlm.nih.gov/pubmed/9727058
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