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Induction of antiphospholipid autoantibodies by immunization with beta 2 glycoprotein I (apolipoprotein H).
A subset of patients with systemic lupus erythematosus has autoantibodies to acidic phospholipids. Since lipids are poor immunogens, the mechanism responsible for the induction of these antibodies is unclear. Immunization of a normal rabbit and normal mice with purified human beta 2-glycoprotein I (...
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Main Authors: | , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
1992
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC329971/ https://ncbi.nlm.nih.gov/pubmed/1522219 |
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