Induction of antiphospholipid autoantibodies by immunization with beta 2 glycoprotein I (apolipoprotein H).

A subset of patients with systemic lupus erythematosus has autoantibodies to acidic phospholipids. Since lipids are poor immunogens, the mechanism responsible for the induction of these antibodies is unclear. Immunization of a normal rabbit and normal mice with purified human beta 2-glycoprotein I (...

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Publié dans:	J Clin Invest
Auteurs principaux:	Gharavi, A E, Sammaritano, L R, Wen, J, Elkon, K B
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Clinical Investigation 1992
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329971/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1522219/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115927
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