Induction of antiphospholipid autoantibodies by immunization with beta 2 glycoprotein I (apolipoprotein H).
A subset of patients with systemic lupus erythematosus has autoantibodies to acidic phospholipids. Since lipids are poor immunogens, the mechanism responsible for the induction of these antibodies is unclear. Immunization of a normal rabbit and normal mice with purified human beta 2-glycoprotein I (...
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| Опубликовано в:: | J Clin Invest |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Clinical Investigation
1992
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329971/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1522219/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115927 |
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