Retinoids increase human apo C-III expression at the transcriptional level via the retinoid X receptor. Contribution to the hypertriglyceridemic action of retinoids.

Hypertriglyceridemia is a metabolic complication of retinoid therapy. In this study, we analyzed whether retinoids increase the expression of apo C-III, an antagonist of plasma triglyceride catabolism. In men, isotretinoin treatment (80 mg/d; 5 d) resulted in elevated plasma apo C-III, but not apo E...

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Autori principali: Vu-Dac, N, Gervois, P, Torra, I P, Fruchart, J C, Kosykh, V, Kooistra, T, Princen, H M, Dallongeville, J, Staels, B
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1998
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC508923/
https://ncbi.nlm.nih.gov/pubmed/9691099
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