Maintenance of bile acid synthesis and cholesterol 7 alpha-hydroxylase activity in cultured rat hepatocytes.

Por Princen, H M, Meijer, P
Publicado em 1990

Dexamethasone regulates bile acid synthesis in monolayer cultures of rat hepatocytes by induction of cholesterol 7 alpha-hydroxylase.

Por Princen, H M, Meijer, P, Hofstee, B
Publicado em 1989

Butyrate stimulates the secretion of apolipoprotein (apo) A-I and apo B100 by the human hepatoma cell line Hep G2. Induction of apo A-I mRNA with no change of apo B100 mRNA.

Por Kaptein, A, Roodenburg, L, Princen, H M
Publicado em 1991

Differential feedback regulation of cholesterol 7 alpha-hydroxylase mRNA and transcriptional activity by rat bile acids in primary monolayer cultures of rat hepatocytes.

Por Twisk, J, Lehmann, E M, Princen, H M
Publicado em 1993

Selective inhibition of mitochondrial 27-hydroxylation of bile acid intermediates and 25-hydroxylation of vitamin D3 by cyclosporin A.

Por Dahlbäck-Sjöberg, H, Björkhem, I, Princen, H M
Publicado em 1993

Suppression of sterol 27-hydroxylase mRNA and transcriptional activity by bile acids in cultured rat hepatocytes.

Por Twisk, J, de Wit, E C, Princen, H M
Publicado em 1995

Cellular free cholesterol in Hep G2 cells is only partially available for down-regulation of low-density-lipoprotein receptor activity.

Por Havekes, L M, de Wit, E C, Princen, H M
Publicado em 1987

Cyclosporin A blocks bile acid synthesis in cultured hepatocytes by specific inhibition of chenodeoxycholic acid synthesis.

Por Princen, H M, Meijer, P, Wolthers, B G, Vonk, R J, Kuipers, F
Publicado em 1991

Ketoconazole blocks bile acid synthesis in hepatocyte monolayer cultures and in vivo in rat by inhibiting cholesterol 7 alpha-hydroxylase.

Por Princen, H M, Huijsmans, C M, Kuipers, F, Vonk, R J, Kempen, H J
Publicado em 1986

The influence of glucocorticoid on the fibrinogen messenger RNA content of rat liver in vivo and in hepatocyte suspension culture.

Por Princen, H M, Moshage, H J, de Haard, H J, van Gemert, P J, Yap, S H
Publicado em 1984

Heterogeneity of rat liver parenchyma in cholesterol 7 alpha-hydroxylase and bile acid synthesis.

Por Ugele, B, Kempen, H J, Kempen, J M, Gebhardt, R, Meijer, P, Burger, H J, Princen, H M
Publicado em 1991

Retinoids increase human apo C-III expression at the transcriptional level via the retinoid X receptor. Contribution to the hypertriglyceridemic action of retinoids.

Por Vu-Dac, N, Gervois, P, Torra, I P, Fruchart, J C, Kosykh, V, Kooistra, T, Princen, H M, Dallongeville, J, Staels, B
Publicado em 1998

Lipoprotein cholesterol uptake mediates up-regulation of bile-acid synthesis by increasing cholesterol 7alpha-hydroxylase but not sterol 27-hydroxylase gene expression in cultured...

Por Post, S M, Twisk, J, van der Fits, L, de Wit, E C, Hoekman, M F, Mager, W H, Princen, H M
Publicado em 1999

Heterogeneous expression of cholesterol 7 alpha-hydroxylase and sterol 27-hydroxylase genes in the rat liver lobulus.

Por Twisk, J, Hoekman, M F, Mager, W H, Moorman, A F, de Boer, P A, Scheja, L, Princen, H M, Gebhardt, R
Publicado em 1995

Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease

Por Dewey, F.E., Gusarova, V., Dunbar, R.L., O’Dushlaine, C., Schurmann, C., Gottesman, O., McCarthy, S., Van Hout, C.V., Bruse, S., Dansky, H.M., Leader, J.B., Murray, M.F., Ritchie, M.D., Kirchner, H.L., Habegger, L., Lopez, A., Penn, J., Zhao, A., Shao, W., Stahl, N., Murphy, A.J., Hamon, S., Bouzelmat, A., Zhang, R., Shumel, B., Pordy, R., Gipe, D., Herman, G.A., Sheu, W.H.H., Lee, I-T., Liang, K.-W., Guo, X., Rotter, J.I., Chen, Y.-D.I., Kraus, W.E., Shah, S.H., Damrauer, S., Small, A., Rader, D.J., Wulff, A.B., Nordestgaard, B.G., Tybjærg-Hansen, A., van den Hoek, A.M., Princen, H.M.G., Ledbetter, D.H., Carey, D.J., Overton, J.D., Reid, J.G., Sasiela, W.J., Banerjee, P., Shuldiner, A.R., Borecki, I.B., Teslovich, T.M., Yancopoulos, G.D., Mellis, S.J., Gromada, J., Baras, A.
Publicado no N Engl J Med (2017)