Characterization of a novel subset of CD8(+) T cells that expands in patients receiving interleukin-12.

IL-12 has significant antitumor activity in mice that may be mediated by CD8(+) T cells. We show in this report that repeated subcutaneous injections of IL-12 in patients with cancer resulted in the selective expansion of a subset of peripheral blood CD8(+) T cells. This T cell subset expressed high...

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Detalhes bibliográficos
Main Authors: Gollob, J A, Schnipper, C P, Orsini, E, Murphy, E, Daley, J F, Lazo, S B, Frank, D A, Neuberg, D, Ritz, J
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC508917/
https://ncbi.nlm.nih.gov/pubmed/9691093
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