Abrogation of autoimmune diabetes in nonobese diabetic mice and protection against effector lymphocytes by transgenic paracrine TGF-beta1.

Paracrine effect of transforming growth factor-beta1 (TGF-beta1) on autoimmune insulitis and diabetes was studied by transgenic production of the active form of porcine TGF-beta1 (pTGF-beta1) in pancreatic islet (islet) alpha cells in nonobese diabetic (NOD) mice under the control of rat glucagon pr...

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Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: Moritani, M, Yoshimoto, K, Wong, S F, Tanaka, C, Yamaoka, T, Sano, T, Komagata, Y, Miyazaki, J, Kikutani, H, Itakura, M
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1998
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508910/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9691086/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI2992
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