Abrogation of autoimmune diabetes in nonobese diabetic mice and protection against effector lymphocytes by transgenic paracrine TGF-beta1.

Paracrine effect of transforming growth factor-beta1 (TGF-beta1) on autoimmune insulitis and diabetes was studied by transgenic production of the active form of porcine TGF-beta1 (pTGF-beta1) in pancreatic islet (islet) alpha cells in nonobese diabetic (NOD) mice under the control of rat glucagon pr...

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Detalhes bibliográficos
Main Authors: Moritani, M, Yoshimoto, K, Wong, S F, Tanaka, C, Yamaoka, T, Sano, T, Komagata, Y, Miyazaki, J, Kikutani, H, Itakura, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC508910/
https://ncbi.nlm.nih.gov/pubmed/9691086
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