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Effects of flavopiridol on critical regulation pathways of CD133(high)/CD44(high) lung cancer stem cells
BACKGROUND: Flavopiridol a semisynthetic flavone that inhibits cyclin-dependent kinases (CDKs) and has growth-inhibitory activity and induces a blockade of cell-cycle progression at G1-phase and apoptosis in numerous human tumor cell lines and is currently under investigation in phase II clinical tr...
में बचाया:
| में प्रकाशित: | Medicine (Baltimore) |
|---|---|
| मुख्य लेखकों: | , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Wolters Kluwer Health
2016
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5089099/ https://ncbi.nlm.nih.gov/pubmed/27787370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000005150 |
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