Effects of flavopiridol on critical regulation pathways of CD133(high)/CD44(high) lung cancer stem cells

BACKGROUND: Flavopiridol a semisynthetic flavone that inhibits cyclin-dependent kinases (CDKs) and has growth-inhibitory activity and induces a blockade of cell-cycle progression at G1-phase and apoptosis in numerous human tumor cell lines and is currently under investigation in phase II clinical tr...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Medicine (Baltimore)
Autores principales: Bozok Cetintas, Vildan, Acikgoz, Eda, Yigitturk, Gurkan, Demir, Kenan, Oktem, Gulperi, Tezcanli Kaymaz, Burçin, Oltulu, Fatih, Aktug, Huseyin
Formato: Artigo
Lenguaje:Inglês
Publicado: Wolters Kluwer Health 2016
Materias:
5700
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5089099/
https://ncbi.nlm.nih.gov/pubmed/27787370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000005150
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares