beta2-Microglobulin mutations, HLA class I antigen loss, and tumor progression in melanoma.

The potential negative impact of HLA class I antigen abnormalities on the outcome of T cell-based immunotherapy of melanoma has prompted us to investigate the mechanisms underlying lack of HLA class I antigen expression by melanoma cell lines Me18105, Me9923, and Me1386. Distinct mutations in the be...

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Pubblicato in:	J Clin Invest
Autori principali:	Hicklin, D J, Wang, Z, Arienti, F, Rivoltini, L, Parmiani, G, Ferrone, S
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1998
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508863/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9637706/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI498
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