Lack of HLA class I antigen expression by cultured melanoma cells FO-1 due to a defect in B2m gene expression.
The melanoma cell line FO-1 does not express HLA class I antigens and does not acquire them on the cell surface after incubation with IFN-gamma. Immunochemical studies showed that FO-1 cells synthesize HLA class I heavy chain, but do not synthesize beta 2-microglobulin (beta 2-mu). The latter abnorm...
שמור ב:
| הוצא לאור ב: | J Clin Invest |
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| Principais autores: | , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Clinical Investigation
1991
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295046/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1898655/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114984 |
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