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beta2-Microglobulin mutations, HLA class I antigen loss, and tumor progression in melanoma.

The potential negative impact of HLA class I antigen abnormalities on the outcome of T cell-based immunotherapy of melanoma has prompted us to investigate the mechanisms underlying lack of HLA class I antigen expression by melanoma cell lines Me18105, Me9923, and Me1386. Distinct mutations in the be...

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Detalles Bibliográficos
Main Authors: Hicklin, D J, Wang, Z, Arienti, F, Rivoltini, L, Parmiani, G, Ferrone, S
Formato: Artigo
Idioma:Inglês
Publicado: 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC508863/
https://ncbi.nlm.nih.gov/pubmed/9637706
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