The PML/RARalpha fusion protein inhibits tumor necrosis factor-alpha-induced apoptosis in U937 cells and acute promyelocytic leukemia blasts.

Ítems similars

• Effects on differentiation by the promyelocytic leukemia PML/RARalpha protein depend on the fusion of the PML protein dimerization and RARalpha DNA binding domains.
  per: Grignani, F, et al.
  Publicat: (1996)
• Opposite effects of the acute promyelocytic leukemia PML-retinoic acid receptor alpha (RAR alpha) and PLZF-RAR alpha fusion proteins on retinoic acid signalling.
  per: Ruthardt, M, et al.
  Publicat: (1997)
• Expression pattern of the RAR alpha-PML fusion gene in acute promyelocytic leukemia.
  per: Alcalay, M, et al.
  Publicat: (1992)
• Genomic variability and alternative splicing generate multiple PML/RAR alpha transcripts that encode aberrant PML proteins and PML/RAR alpha isoforms in acute promyelocytic leukaemia.
  per: Pandolfi, P P, et al.
  Publicat: (1992)
• Additive antisense effects of different PNAs on the in vitro translation of the PML/RARalpha gene.
  per: Mologni, L, et al.
  Publicat: (1998)