Defective insulin secretion in hepatocyte nuclear factor 1alpha-deficient mice.

Mutations in the gene for the transcription factor hepatocyte nuclear factor (HNF) 1alpha cause maturity-onset diabetes of the young (MODY) 3, a form of diabetes that results from defects in insulin secretion. Since the nature of these defects has not been defined, we compared insulin secretory func...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Pontoglio, M, Sreenan, S, Roe, M, Pugh, W, Ostrega, D, Doyen, A, Pick, A J, Baldwin, A, Velho, G, Froguel, P, Levisetti, M, Bonner-Weir, S, Bell, G I, Yaniv, M, Polonsky, K S
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1998
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508809/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9593777/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI2548
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