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HNF1α controls renal glucose reabsorption in mouse and man

Recently it has been shown that dominant mutations in the human hepatocyte nuclear factor 1 α (HNF1α) gene, encoding for a homeoprotein that is expressed in liver, kidney, pancreas and intestine, result in maturity onset diabetes of the young type 3 (MODY3). HNF1α-null mice are diabetic, but at the...

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Главные авторы: Pontoglio, Marco, Prié, Dominique, Cheret, Claire, Doyen, Antonia, Leroy, Christine, Froguel, Philippe, Velho, Gilberto, Yaniv, Moshe, Friedlander, Gérard
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2000
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1083745/
https://ncbi.nlm.nih.gov/pubmed/11269503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvd071
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