Transcriptome profiling of patient-specific human iPSC-cardiomyocytes predicts individual drug safety and efficacy responses in vitro

Understanding individual susceptibility to drug-induced cardiotoxicity is key to improving patient safety and preventing drug attrition. Human induced pluripotent stem cells (hiPSCs) enable the study of pharmacological and toxicological responses in patient-specific cardiomyocytes (CMs), and may ser...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Cell Stem Cell
Autors principals: Matsa, Elena, Burridge, Paul W., Yu, Kun-Hsing, Ahrens, John H., Termglinchan, Vittavat, Wu, Haodi, Liu, Chun, Shukla, Praveen, Sayed, Nazish, Churko, Jared M., Shao, Ningyi, Woo, Nicole A., Chao, Alexander S., Gold, Joseph D., Karakikes, Ioannis, Snyder, Michael P., Wu, Joseph C.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087997/
https://ncbi.nlm.nih.gov/pubmed/27545504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2016.07.006
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars