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Accumulation of long-chain bases in yeast promotes their conversion to a long-chain base vinyl ether
Long-chain bases (LCBs) are the precursors to ceramide and sphingolipids in eukaryotic cells. They are formed by the action of serine palmitoyl-CoA transferase (SPT), a complex of integral membrane proteins located in the endoplasmic reticulum. SPT activity is negatively regulated by Orm proteins to...
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| Udgivet i: | J Lipid Res |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society for Biochemistry and Molecular Biology
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5087871/ https://ncbi.nlm.nih.gov/pubmed/27561298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M070748 |
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