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Following the flux of long-chain bases through the sphingolipid pathway in vivo using mass spectrometry

Sphingolipids are essential components of the plasma membrane. Their synthesis is tightly controlled by regulatory proteins, which impinge on the rate-limiting step of the pathway, the condensation of serine and palmitoyl-CoA to long-chain base (LCB). The subsequent conversion of LCB to ceramide by...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Martínez-Montañés, Fernando, Schneiter, Roger
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4847623/
https://ncbi.nlm.nih.gov/pubmed/26977056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.D066472
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