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Different rates of flux through the biosynthetic pathway for long-chain versus very-long-chain sphingolipids

The backbone of all sphingolipids (SLs) is a sphingoid long-chain base (LCB) to which a fatty acid is N-acylated. Considerable variability exists in the chain length and degree of saturation of both of these hydrophobic chains, and recent work has implicated ceramides with different LCBs and N-acyl...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Zelnik, Iris D., Volpert, Giora, Viiri, Leena E., Kauhanen, Dimple, Arazi, Tamar, Aalto-Setälä, Katriina, Laaksonen, Reijo, Futerman, Anthony H.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7529049/
https://ncbi.nlm.nih.gov/pubmed/32651186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.RA120000984
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