Overexpression of myocardial Gsalpha prevents full expression of catecholamine desensitization despite increased beta-adrenergic receptor kinase.

Inotropic and chronotropic responses to catecholamines in young adult transgenic mice overexpressing myocardial Gsalpha are enhanced. One might predict that over the life of the animal, this chronically enhanced beta-adrenergic receptor stimulation would result in homologous catecholamine desensitiz...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Clin Invest
Egile Nagusiak: Vatner, D E, Asai, K, Iwase, M, Ishikawa, Y, Wagner, T E, Shannon, R P, Homcy, C J, Vatner, S F
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 1998
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508778/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9576756/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI1530
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