Chondroitin 4-O-Sulfotransferase Is Indispensable for Sulfation of Chondroitin and Plays an Important Role in Maintaining Normal Life Span and Oxidative Stress Responses in Nematodes

Chondroitin sulfate (CS)/chondroitin (Chn) chains are indispensable for embryonic cell division and cytokinesis in the early developmental stages in Caenorhabditis elegans and mice, whereas heparan sulfate (HS) is essential for axon guidance during nervous system development. These data indicate tha...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Izumikawa, Tomomi, Dejima, Katsufumi, Watamoto, Yukiko, Nomura, Kazuko H., Kanaki, Nanako, Rikitake, Marika, Tou, Mai, Murata, Daisuke, Yanagita, Eri, Kano, Ai, Mitani, Shohei, Nomura, Kazuya, Kitagawa, Hiroshi
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2016
Sujets:
Glycobiology and Extracellular Matrices
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087745/
https://ncbi.nlm.nih.gov/pubmed/27645998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.757328
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