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Down-regulation of Chondroitin 4-O-Sulfotransferase-1 by Wnt Signaling Triggers Diffusion of Wnt-3a

During metazoan development, Wnt molecules are secreted from Wnt-producing cells, diffuse to target cells, and determine cell fates; therefore, Wnt secretion is tightly regulated. However, the molecular mechanisms controlling Wnt diffusion are not fully elucidated. The specific chondroitin sulfate (...

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Main Authors: Nadanaka, Satomi, Kinouchi, Hiroki, Taniguchi-Morita, Kayo, Tamura, Jun-ichi, Kitagawa, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039320/
https://ncbi.nlm.nih.gov/pubmed/21123170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.155093
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