UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase is indispensable for oogenesis, oocyte-to-embryo transition, and larval development of the nematode Caenorhabditis elegans

N-linked glycosylation of proteins is the most common post-translational modification of proteins. The enzyme UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1) catalyses the first step of N-glycosylation, and DPAGT1 knockout is embryonic lethal in mice. In thi...

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Veröffentlicht in:Glycobiology
Hauptverfasser: Kanaki, Nanako, Matsuda, Ayako, Dejima, Katsufumi, Murata, Daisuke, Nomura, Kazuko H, Ohkura, Takashi, Gengyo-Ando, Keiko, Yoshina, Sawako, Mitani, Shohei, Nomura, Kazuya
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668254/
https://ncbi.nlm.nih.gov/pubmed/30445613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwy104
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