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Up-regulation of N-cadherin by Collagen I-activated Discoidin Domain Receptor 1 in Pancreatic Cancer Requires the Adaptor Molecule Shc1

Pancreatic ductal adenocarcinomas are highly malignant cancers characterized by extensive invasion into surrounding tissues, metastasis to distant organs, and a limited response to therapy. A main feature of pancreatic ductal adenocarcinomas is desmoplasia, which leads to extensive deposition of col...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Huang, Huocong, Svoboda, Robert A., Lazenby, Audrey J., Saowapa, Jintana, Chaika, Nina, Ding, Ke, Wheelock, Margaret J., Johnson, Keith R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087738/
https://ncbi.nlm.nih.gov/pubmed/27605668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.740605
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