Signaling adaptor ShcD suppresses extracellular signal-regulated kinase (Erk) phosphorylation distal to the Ret and Trk neurotrophic receptors

Proteins of the Src homology and collagen (Shc) family are typically involved in signal transduction events involving Ras/MAPK and PI3K/Akt pathways. In the nervous system, they function proximal to the neurotrophic factors that regulate cell survival, differentiation, and neuron-specific characteri...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Wills, Melanie K. B., Keyvani Chahi, Ava, Lau, Hayley R., Tilak, Manali, Guild, Brianna D., New, Laura A., Lu, Peihua, Jacquet, Kévin, Meakin, Susan O., Bisson, Nicolas, Jones, Nina
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2017
Schlagworte:
Signal Transduction
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392570/
https://ncbi.nlm.nih.gov/pubmed/28213521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.770511
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