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The ShcD signaling adaptor facilitates ligand-independent phosphorylation of the EGF receptor
Proto-oncogenic Src homology and collagen (Shc) proteins have been considered archetypal adaptors of epidermal growth factor receptor (EGFR)–mediated signaling. We report that in addition to its role as an EGFR-binding partner and Grb2 platform, ShcD acts noncanonically to promote phosphorylation of...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The American Society for Cell Biology
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3952845/ https://ncbi.nlm.nih.gov/pubmed/24430869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-08-0434 |
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