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Targeting Liver Fibrosis with a Cell-penetrating Protease-activated Receptor-2 (PAR2) Pepducin

Chronic liver inflammation and fibrosis in nonalcoholic steatohepatitis can lead to cirrhosis and liver failure for which there are currently no approved treatments. Protease-activated receptor-2 (PAR2) is an emerging new target expressed on liver stellate cells and hepatocytes that regulates the re...

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Foilsithe in:J Biol Chem
Main Authors: Shearer, Andrew M., Rana, Rajashree, Austin, Karyn, Baleja, James D., Nguyen, Nga, Bohm, Andrew, Covic, Lidija, Kuliopulos, Athan
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087736/
https://ncbi.nlm.nih.gov/pubmed/27613872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.732743
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