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Endo-lysosomal TRP mucolipin-1 channels trigger global ER Ca(2+) release and Ca(2+) influx
Transient receptor potential (TRP) mucolipins (TRPMLs), encoded by the MCOLN genes, are patho-physiologically relevant endo-lysosomal ion channels crucial for membrane trafficking. Several lines of evidence suggest that TRPMLs mediate localised Ca(2+) release but their role in Ca(2+) signalling is n...
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| Publicado no: | J Cell Sci |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5087663/ https://ncbi.nlm.nih.gov/pubmed/27577094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.190322 |
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