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The lysosomotrope GPN mobilises Ca(2+) from acidic organelles

Lysosomes are acidic Ca(2+) stores often mobilised in conjunction with endoplasmic reticulum (ER) Ca(2+) stores. Glycyl-L-phenylalanine 2-naphthylamide (GPN) is a widely used lysosomotropic agent that evokes cytosolic Ca(2+) signals in many cells. However, whether these signals are the result of a p...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Cell Sci
Prif Awduron: Yuan, Yu, Kilpatrick, Bethan S., Gerndt, Susanne, Bracher, Franz, Grimm, Christian, Schapira, Anthony H., Patel, Sandip
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Company of Biologists Ltd 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7972315/
https://ncbi.nlm.nih.gov/pubmed/33602742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.256578
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