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Essential role of the Dishevelled DEP domain in a Wnt-dependent human-cell-based complementation assay
Dishevelled (DVL) assembles Wnt signalosomes through dynamic head-to-tail polymerisation by means of its DIX domain. It thus transduces Wnt signals to cytoplasmic effectors including β-catenin, to control cell fates during normal development, tissue homeostasis and also in cancer. To date, most func...
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| Veröffentlicht in: | J Cell Sci |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Company of Biologists Ltd
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5087658/ https://ncbi.nlm.nih.gov/pubmed/27744318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.195685 |
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