Haspin kinase regulates microtubule-organizing center clustering and stability through Aurora kinase C in mouse oocytes

Meiotic oocytes lack classic centrosomes and, therefore, bipolar spindle assembly depends on clustering of acentriolar microtubule-organizing centers (MTOCs) into two poles. However, the molecular mechanism regulating MTOC assembly into two poles is not fully understood. The kinase haspin (also know...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Balboula, Ahmed Z., Nguyen, Alexandra L., Gentilello, Amanda S., Quartuccio, Suzanne M., Drutovic, David, Solc, Petr, Schindler, Karen
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087654/
https://ncbi.nlm.nih.gov/pubmed/27562071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.189340
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