TRIM17 contributes to autophagy of midbodies while actively sparing other targets from degradation

TRIM proteins contribute to selective autophagy, a process whereby cells target specific cargo for autophagic degradation. In a previously reported screen, TRIM17 acted as a prominent inhibitor of bulk autophagy, unlike the majority of TRIMs, which had positive roles. Nevertheless, TRIM17 showed bio...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Mandell, Michael A., Jain, Ashish, Kumar, Suresh, Castleman, Moriah J., Anwar, Tahira, Eskelinen, Eeva-Liisa, Johansen, Terje, Prekeris, Rytis, Deretic, Vojo
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087653/
https://ncbi.nlm.nih.gov/pubmed/27562068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.190017
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