טוען...
Gα12 is required for renal cystogenesis induced by Pkd1 inactivation
Mutation of PKD1, encoding the protein polycystin-1 (PC1), is the main cause of autosomal dominant polycystic kidney disease (ADPKD). The signaling pathways downstream of PC1 in ADPKD are still not fully understood. Here, we provide genetic evidence for the necessity of Gα12 (encoded by Gna12, herea...
שמור ב:
הוצא לאור ב: | J Cell Sci |
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Main Authors: | , , , , , , , , , , , , , |
פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
The Company of Biologists Ltd
2016
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נושאים: | |
גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5087651/ https://ncbi.nlm.nih.gov/pubmed/27505895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.190496 |
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