CD8(+) lymphocytes are required to maintain virus suppression in SIV-infected macaques treated with short-term antiretroviral therapy

Infection with HIV persists despite suppressive antiretroviral therapy (ART) and treatment interruption results in rapid viral rebound. Antibody-mediated CD8(+) lymphocyte depletion in simian immunodeficiency virus (SIV)-infected rhesus macaques (RMs) shows these cells contribute to virus control in...

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Publicado no:Immunity
Main Authors: Cartwright, Emily K., Spicer, Lori, Smith, S. Abigail, Lee, David, Fast, Randy, Paganini, Sara, Lawson, Benton O., Nega, Melon, Easley, Kirk, Schmitz, Joern E., Bosinger, Steven E., Paiardini, Mirko, Chahroudi, Ann, Vanderford, Thomas H., Estes, Jacob D., Lifson, Jeffrey D., Derdeyn, Cynthia A., Silvestri, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087330/
https://ncbi.nlm.nih.gov/pubmed/27653601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2016.08.018
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