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Caloric restriction reverses hepatic insulin resistance in aging rats by decreasing visceral fat.
Hyperinsulinemia and increased visceral/abdominal fat (VF) are common features of human aging. To examine the relationships among VF, peripheral, and hepatic insulin sensitivity, we studied 4- and 18-mo-old male Sprague-Dawley rats (n = 42) fed ad libitum (4 AL and 18 AL) or moderately calorie restr...
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| Publicado no: | J Clin Invest |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508712/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9525977/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI485 |
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