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Leptin selectively decreases visceral adiposity and enhances insulin action.
Intraabdominal adiposity and insulin resistance are risk factors for diabetes mellitus, dyslipidemia, arteriosclerosis, and mortality. Leptin, a fat-derived protein encoded by the ob gene, has been postulated to be a sensor of energy storage in adipose tissue capable of mediating a feedback signal t...
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| Publicado no: | J Clin Invest |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508523/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9399957/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119865 |
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