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Thrombomodulin modulates growth of tumor cells independent of its anticoagulant activity.

Thrombomodulin (TM), recognized as an essential vessel wall cofactor of the antithrombotic mechanism, is also expressed by a wide range of tumor cells. Tumor cell lines subcloned from four patients with malignant melanoma displayed a negative correlation between TM expression and cell proliferation...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Zhang, Y, Weiler-Guettler, H, Chen, J, Wilhelm, O, Deng, Y, Qiu, F, Nakagawa, K, Klevesath, M, Wilhelm, S, Böhrer, H, Nakagawa, M, Graeff, H, Martin, E, Stern, D M, Rosenberg, R D, Ziegler, R, Nawroth, P P
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1998
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508707/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9525972/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI925
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