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Release of thrombomodulin from endothelial cells by concerted action of TNF-alpha and neutrophils: in vivo and in vitro studies.

Inflammatory cytokines decrease the expression of thrombomodulin (TM) on the endothelial cell surface by suppression of TM transcription and translation or internalization with subsequent degradation. Nevertheless, elevated serum TM levels are found in diseases associated with systemical or locally...

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Détails bibliographiques
Auteurs principaux: Boehme, M W, Deng, Y, Raeth, U, Bierhaus, A, Ziegler, R, Stremmel, W, Nawroth, P P
Format: Artigo
Langue:Inglês
Publié: 1996
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1383979/
https://ncbi.nlm.nih.gov/pubmed/8666425
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