Essential protective role of tumor necrosis factor receptor 2 in neurodegeneration

Despite the recognized role of tumor necrosis factor (TNF) in inflammation and neuronal degeneration, anti-TNF therapeutics failed to treat neurodegenerative diseases. Animal disease models had revealed the antithetic effects of the two TNF receptors (TNFR) in the central nervous system, whereby TNF...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Dong, Yun, Fischer, Roman, Naudé, Petrus J. W., Maier, Olaf, Nyakas, Csaba, Duffey, Maëlle, Van der Zee, Eddy A., Dekens, Doortje, Douwenga, Wanda, Herrmann, Andreas, Guenzi, Eric, Kontermann, Roland E., Pfizenmaier, Klaus, Eisel, Ulrich L. M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087045/
https://ncbi.nlm.nih.gov/pubmed/27791020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1605195113
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