Enhanced expression of p53 and apoptosis induced by blockade of the vacuolar proton ATPase in cardiomyocytes.

Activation of the vacuolar proton ATPase (VPATPase) has been implicated in the prevention of apoptosis in neutrophils and adult cardiac myocytes. To determine the role of the VPATPase in apoptosis of cardiac myocytes, we used a potent and specific inhibitor of the VPATPase, bafilomycin A1. Bafilomyc...

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Bibliografiska uppgifter
Huvudupphovsmän: Long, X, Crow, M T, Sollott, S J, O'Neill, L, Menees, D S, de Lourdes Hipolito, M, Boluyt, M O, Asai, T, Lakatta, E G
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1998
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC508701/
https://ncbi.nlm.nih.gov/pubmed/9502788
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