Enhanced expression of p53 and apoptosis induced by blockade of the vacuolar proton ATPase in cardiomyocytes.

Activation of the vacuolar proton ATPase (VPATPase) has been implicated in the prevention of apoptosis in neutrophils and adult cardiac myocytes. To determine the role of the VPATPase in apoptosis of cardiac myocytes, we used a potent and specific inhibitor of the VPATPase, bafilomycin A1. Bafilomyc...

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書誌詳細
主要な著者: Long, X, Crow, M T, Sollott, S J, O'Neill, L, Menees, D S, de Lourdes Hipolito, M, Boluyt, M O, Asai, T, Lakatta, E G
フォーマット: Artigo
言語:Inglês
出版事項: 1998
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC508701/
https://ncbi.nlm.nih.gov/pubmed/9502788
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