Notch3 drives development and progression of cholangiocarcinoma

The prognosis of cholangiocarcinoma (CC) is dismal. Notch has been identified as a potential driver; forced exogenous overexpression of Notch1 in hepatocytes results in the formation of biliary tumors. In human disease, however, it is unknown which components of the endogenously signaling pathway ar...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Guest, Rachel V., Boulter, Luke, Dwyer, Benjamin J., Kendall, Timothy J., Man, Tak-Yung, Minnis-Lyons, Sarah E., Lu, Wei-Yu, Robson, Andrew J., Gonzalez, Sofia Ferreira, Raven, Alexander, Wojtacha, Davina, Morton, Jennifer P., Komuta, Mina, Roskams, Tania, Wigmore, Stephen J., Sansom, Owen J., Forbes, Stuart J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2016
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5086988/
https://ncbi.nlm.nih.gov/pubmed/27791012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1600067113
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg