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Hepatic progenitor cells of biliary origin with liver repopulation capacity
Hepatocytes and cholangiocytes self renew following liver injury. Following severe injury hepatocytes are increasingly senescent, whether Hepatic Progenitor Cells (HPCs) then contribute to liver regeneration is unclear. Here, we describe a mouse model where Mdm2 is inducibly deleted in over 98% of h...
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Published in: | Nat Cell Biol |
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Main Authors: | , , , , , , , , , , , , , , , , , , , |
Format: | Artigo |
Language: | Inglês |
Published: |
2015
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4612439/ https://ncbi.nlm.nih.gov/pubmed/26192438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3203 |
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